Tuesday, September 8, 2009

Limeriks of Learning

Two biochemically inspired limericks by Kristopher Hite

The proteosome proceeds to forage
transforming proteins to porridge
if ubiquitin tagged
Then subsequently bagged
catabolized and placed into storage

Hec1 and Nuf2 unite
together coiled-up tight
microtubule bound
never coming unwound
to align all the chromosomes right

inspired by the following research...

Yao, T. (2000). Cyclization of Polyubiquitin by the E2-25K Ubiquitin Conjugating Enzyme Journal of Biological Chemistry, 275 (47), 36862-36868 DOI: 10.1074/jbc.M006050200

GUIMARAES, G., DONG, Y., MCEWEN, B., & DELUCA, J. (2008). Kinetochore-Microtubule Attachment Relies on the Disordered N-Terminal Tail Domain of Hec1 Current Biology, 18 (22), 1778-1784 DOI: 10.1016/j.cub.2008.08.012
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